Susan S Taylor Selected Research

Holoenzymes

10/2021	Gαs-Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling.
12/2020	Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
12/2016	Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation.

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Susan S Taylor Research Topics

Disease

7	Neoplasms (Cancer) 01/2021 - 10/2006
3	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2019
3	Acrodysostosis 10/2021 - 12/2016
3	Cushing Syndrome 10/2021 - 01/2019
3	Fibrolamellar hepatocellular carcinoma 12/2020 - 01/2018
3	Lymphoma (Lymphomas) 10/2015 - 11/2012
2	Carney Complex 10/2021 - 01/2021
2	Liver Neoplasms (Liver Cancer) 01/2021 - 01/2020
2	Adrenocortical Adenoma (Disease, Conn's) 01/2021 - 01/2019
2	Ischemia 01/2018 - 10/2013
1	Mental Disorders (Mental Disorder) 01/2022
1	Pituitary Neoplasms (Pituitary Adenoma) 01/2021
1	Melanoma (Melanoma, Malignant) 01/2019
1	Bone Resorption 01/2018
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2018
1	Stroke (Strokes) 01/2018
1	Ischemic Stroke 01/2018
1	Insulin Resistance 01/2016
1	Obesity 01/2016
1	Weight Gain 01/2016
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2016
1	B-Cell Lymphoma (Lymphoma, B Cell) 10/2015
1	Communicable Diseases (Infectious Diseases) 10/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 08/2015
1	familial dilated cardiomyopathy 03/2015
1	Infarction (Infarctions) 10/2013
1	Reperfusion Injury 10/2013
1	Malaria 08/2012
1	Multiple Endocrine Neoplasia Type 2b (MEN 3) 10/2006
1	Multiple Endocrine Neoplasia Type 2a (MEN 2) 10/2006
1	Type 2 Diabetes Mellitus (MODY) 09/2005
1	Disease Susceptibility (Diathesis) 04/2003

Drug/Important Bio-Agent (IBA)

15	Phosphotransferases (Kinase)IBA 01/2022 - 04/2003
10	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2021 - 11/2012
6	Proteins (Proteins, Gene)FDA Link 12/2020 - 11/2012
3	Leucine (L-Leucine)FDA Link 01/2022 - 01/2019
3	HoloenzymesIBA 10/2021 - 12/2016
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2021 - 01/2019
2	A Kinase Anchor ProteinsIBA 01/2018 - 04/2003
1	Dopamine (Intropin)FDA LinkGeneric 01/2022
1	GTP Phosphohydrolases (GTPases)IBA 01/2022
1	Glutamic Acid (Glutamate)FDA Link 01/2022
1	NucleotidesIBA 01/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 12/2020
1	Protein Subunits (Protein Subunit)IBA 12/2020
1	Oncogene Proteins (Oncogene Protein)IBA 01/2020
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2019
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2018
1	RANK LigandIBA 01/2018
1	Superoxides (Superoxide)IBA 01/2018
1	HSP40 Heat-Shock ProteinsIBA 01/2018
1	Dynamins (Dynamin)IBA 01/2018
1	Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA 01/2016
1	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 01/2016
1	GlucocorticoidsIBA 10/2015
1	Bcl-2-Like Protein 11IBA 10/2015
1	Cyclic AMP (AMP, Cyclic)IBA 10/2015
1	SolutionsIBA 03/2015
1	phospholambanIBA 03/2015
1	Protein Kinases (Protein Kinase)IBA 02/2015
1	IntegrinsIBA 10/2013
1	Peptides (Polypeptides)IBA 08/2012
1	Protein Isoforms (Isoforms)IBA 08/2012
1	ProteomeIBA 08/2012
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 10/2006
1	beta Adrenergic ReceptorsIBA 09/2005
1	Amino Acids FDA Link 04/2003

Therapy/Procedure

1	Transplantation 01/2016
1	Therapeutics 08/2015